59 year old female with seizures.


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A 60year old female came with complaints of seizures,vomitings,abdominal pain. 


I've been given this case to solve in an attempt to understand the topic of "patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with a diagnosis and treatment plan.


CASE PRESENTATION:


A 60yr old female, who is a housewife presented to casuality on 2ndmarch2022 with

CHEIF COMPLAINTS of 

Involuntary movements of bilateral upper and lower limbs. 


HISTORY OF PRESENT ILLNESS:


Patient was apparently asymptomatic 3days back then she had vomitings 5 to 6 episodes per day which is of non projectile,non bilious,and food particles as contents  associated with abdominal pain which is of diffuse type.

Patient has history of fever which is intermittent, low grade subsided on medications. Not associated with chills and rigors. 

She went to local hospital and then they prescribed medications but even  then vomitings didnt get subsided  

 

1day ago  she developed  involuntary movements of B/L upper and lower limbs  associated with tongue bite, uprolling of eyes, GTCS type  lasting for 2mins associated with involuntary micturition  , post ictal confusion present. Aura absent.


Later on she developed fever which is insidious  in onset gradually progressive not associated with chills and rigor and subsided with medication.


No c/o cold ,cough,headche,trauma,burning micturition.


PAST HISTORY 


No similar complaints in the past.

Not a known case of HTN,DM,ASTHMA,epilepsy,CAD


PERSONAL HISTORY 


Marital status - married 

Occupation -  House wife

Appetite - Normal 

Diet -  vegetarian

Bowel and bladder movements - normal

Addictions - no addictions

.

FAMILY HISTORY


No significant family history .


GENERAL EXAMINATION :


Patient is conscious , in coherant ,non cooperative


No pallor,No icterus , cyanosis , lymphadenopathy, edema 



VITALS


Temp:98F

BP : 140/ 80mm Hg

PR : 89beats/ MIN

RR : 16/ MIN

SPO2: 98% on RA

GRBS : 160 mg/dl


SYSTEMIC EXAMINATION

CVS : S1, S2 +

RS : BAE + ,Breath sounds on b/l IAA,IMA heard

P/A : soft , nontender 

CNS :Patient is conscious but drowsy

Speech is incoherant

No signs of meningeal irritation


Cranial nerves- NAD 

Motor system: NAD

Sensory system: NAD

GCS-E4V2M6

-                         RIGHT               LEFT

PUPIL.                  RL.             RL

TONE         UL        NORMAL       NORMAL

                     LL        NORMAL       NORMAL

POWER    UL         NORMAL       NORMAL

                    LL         NORMAL       NORMAL                    

REFLEXES  

       a) BICEPS               2+                    2+

       b) TRICEPS            2+                    2+ 

       c) SUPINATOR       2+                    2+

       d) KNEE                   2+                    -

       e) ANKLE                 2+                    2+

       f) PLANTAR        extensor          extensor

INVESTIGATIONS:


Serum electrolytes on 2/03/2022 10:30AM


Serum electrolytes on 2/03/2022 7:30 PM



SERUM ELECTROLYTES
2/3/22

Na+.   126.  K+   3.7.      Cl-97      

3/3/22

         8am.     12pm.      6pm.    

Na+   134.      137.         138

K+.     3 3.        3.4.          3.1

Cl-.     107.        97.         97

4/3/22

Na+.   138      .        

K+.    3.6               

Cl-      102


ABG

PH  7.44

PCO2 24.0

PO2 107

HCO3 16.1

ST HCO3 20.0

HEMOGRAM: 

HB: 13.5

TLC: 16,800

N/L/E/M/B: 86/09/01/05/00

PCV: 38.1

MCV: 80.8

MCH: 28.6

RBC:4.72

RDW-CV :12.6

RDW-SD: 41.7

PS: NC/NC

PLT:-1.1

CUE-

Alb :+

Sugars:nil

Pc:4-5/Hpf 

RBS 164mg/dl




Blood Urea : 16 MG/DL

Serum Creatinine: 0.7

Serum calcium:10.9

Serum phosphate: 2.4

LFT

TB: 1.35

DB: 0.3

SGOT:19

SGOT:25

ALP: 163

TP:7.6

ALBUMIN:4.9

A/G: 1.87

SERUM LIPID PROFILE: 

Total cholesterol:171mg/dl

Triglycerides: 153mg/dl
HDL: 48

LDL:98

VLDL:30

TFT(3/3/22):

T3:0.71

T4;9.10

TSH:4.91


Spot urine sodium  122mmol/L

Spot urinary potassium 21

Serum for osmolality  269mOSM/kg

Urinary chloride  156mmol/L

ECG on 2/03/2022


Chest X-ray


Ultrasound on 3/03/2022



2D Echo


FEVER chart


MDCT Scan Brain -Plain 


 PROVISIONAL DIAGNOSIS

Seizures secondary to hyponatremia


TREATMENT

1. Inj Levipil 1gm in 100ml NS/IV stat

2. Inj Pan 40mg /IV/ Stat

3. 3%Nacl infusion @10ml /hour followed by  4th hourly serum electrolytes.

4. 0.9% NS @75ml/hour.

5. Monitor vital hourly.

6. Strict I/O charting.

7.inj.neomal 100ml/iv if temp >101.1F

8.inj.monocef 1gm /iv /bd.


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